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The maximum dose you can TAKE depends entirely on you and your tolerance level.

The maximum dose that Percocet is AVAILABLE in is 10mg. For me, I generally take between 20-30mg at a time depending on how I feel. But I use a lot of it and have for many years, so my tolerance level is extremely high.

There is no maximum dose of opiate medications (or synthetic or semi-synthetic opiates). There is however, a maximum dosage of APAP (Tylenol or Acetaminophen) of 4 grams or 4,000 mgs daily. Obviously, the higher your tolerance & the longer you've been on the drug, the more of the opiate you must take to maintain pain control.

I currently take Percocet (Oxycodone 10mg, APAP 325mg) 2 pills every 4 hours, max 12 pills per day. That amount is a stregnth that would kill someone who doesnt take them regularly

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14y ago

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