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According to ePocrates, etanercept (Enbrel) has a half-life of 102 hours, which is four and a quarter. Using the rule that 4-5 half-lives are required to reach steady-state, it'd take around 17-21 days for the drug to leave one's system.

This is very approximate, however. Please discuss this with the physician who prescribed this medication.

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17y ago

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