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It can be different from one person to the next, but my experience is as such: I had to detox from methadone to start a Suboxone detox, my last dose of methadone came on a Monday at 10AM, I was to start Suboxone on Thursday morning, the cold turkey off the methadone became a bit much by Wednesday. I shot 2 bags to curb the withdrawals at 4PM on Wednesday and was dosed with 16 mgs OS Suboxone at 8:30AM on Thursday as planned and was not feeling great but was safe from the sickness that comes from taking suboxone to soon after your last push off. Hope that helps a bit.

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13y ago

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