Depending on where in Cincinnati to where in Columbia the trip could take anywhere from 8½ to 9½ hours via Interstate 26 north, 40 East, 75 north.
About 50 minutes.
too long grab a flight
It takes about nine hours to drive from Columbus, Ohio to Columbia, SC on I-77.
Check Mapquest.com
10 hour for a trucker
About 5 hours depending on traffic conditions and where exactly you are in Cincinnati when you start.
It is 717 miles according to Google Maps.
Google Maps estimates the driving time as 3 hours and 32 minutes.
It is 26.6 miles and an estimated 34 minute drive according to Google Maps.
It is 2,371 miles according to Google Maps.
It is 364 miles accordiing to Google Maps.
5 hours and 16 minutes