How many miles between Houston and Vicksburg?

Answer 1

433 miles taking this route:

1. Take U.S. 59 NORTH from Houston to I-20, near Marshall. At JCT I-20, follow signs to I-20 EAST to SHREVEPORT.
2. Take I-20 EAST to Vicksburg via I-220 EAST (EXIT 11 off I-20 in Louisiana) to bypass SHREVEPORT.