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3,040 miles taking this route:

  1. Take I-75 NORTH, from Ft. Myers, to I-10 WEST to TALLAHASSEE off EXIT 435 in Lake City.
  2. Take I-10 WEST all the way across the country to CA-210 WEST to PASADENA off EXIT 77C in California. To bypass New Orleans, take I-12 WEST (EXIT 259B off I-10 in LOUISIANA). To bypass PHOENIX, follow the PHOENIX BYPASS ROUTE (I-8 WEST [EXIT 199 off I-10 in ARIZONA] to AZ-85 NORTH [EXIT 119 off I-8], and then AZ-85 NORTH back up to I-10 WEST towards LOS ANGELES).
  3. Take CA-210/I-210 WEST, around LOS ANGELES, to I-5 NORTH to SACRAMENTO at EXIT 1A.
  4. Take I-5 NORTH to I-580 WEST to San Francisco at EXIT 446.
  5. Take I-580 WEST to I-80 WEST to SAN FRANCISCO at EXIT 19A.
  6. Take I-80 WEST, across the BAY BRIDGE, into San Francisco.
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Q: How many miles from Ft. Myers Florida to San Francisco California?
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