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Yes - in fact the dose size for a dog is up to 2mg/kg (0.9mg/lb) - so for a 75lb dog you are talking approximately 65mg. Yes dogs tolerate a higher dose better than a human does (or they use it less efficiently).

As always, check with a vet.

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15y ago
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11y ago

Benadryl is not a sedative, so this isn't going to work. Benadryl (diphenhydramine) is an anti-histamine with a mild side effect of drowsiness. However, not all dogs show this side effect, and giving more drug may not increase the apparent sedation. Benadryl in high doses can be toxic, so you can't increase the amount to get the drowsiness you want.

If your dog needs sedation, you should speak with your veterinarian - there are several generic drugs that can be prescribed for this on an "as-needed" basis that will give you a much better sedation for a similar price.

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12y ago

It's never a good idea to give your pet a medicine that is not recommended by a vet, especially in the case of human medicine. Giving human medicine to a dog can be harmful and at worse, fatal.

If you believe your dog needs treatment, take it to the vet.

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11y ago

1mg per pound of body weight, so if your dog is 25 lbs give him/her 25mg of Benadryl. Make sure it is ONLY Benadryl (Diphenhydramine) without any other combination of medicine in it.

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Q: May you give your 75 lb dog benadryl without hurting her?
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No! Benadryl is a human drug, for human use only! If you must give your cat medication, take it to a vet and have them diagnose it. The medicine they perscribe may be similar to Benadryl, but it really isn't safe to put it anywhere near a cat.


How much benadryl can you give your 5 lb puppy?

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Can you give Benadryl to dogs indefinitely?

Yes you can give a dog benadryl indefinitely...just make sure that you check with your vet that you are giving the correct dose. You want to give as little as possible, just enough to control the symptoms. You may want to also check with your vet to see if there is another antihistamine that may even work better for your dog. Surprisingly there are many antihistamine that you can get through a prescription from your vet that may even be cheaper than buying benadryl over the counter.An Alternate Answer:Dogs can have 1-2mg of Benadryl per pound, every 8 hours. This can be used to treat allergic reactions, and it also has some anti-anxiety effects. As a general rule, Benadryl is very effective for both dogs and cats, as it is for humans, and, as with humans, the primary side effect is drowsiness, with dogs and cats, as well.


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I have been prescribed codeine and benadryl simultaneously. It may slightly reduce the effectiveness of the codeine, but that's all.


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How much ml dose is 2 mg of benadryl?

Unless you're a veterinarian (which I will assume you aren't since you are asking the internet for dose rates), to prescribe your dog Benadryl would be considered practicing veterinary medicine without a licence. If your dog is sick, take it to the vet. They will prescribe for it what it needs, (which may or may not be benadryl), and tell you how much to give.


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How much Benadryl can a dog take?

If Benadryl is being given to a dog to calm it I have asked my Veterinarian the same question. He told me give the dog 1 wait 30 minutes, give another, wait 30 minutes. Keep going like this till you have the desired effect, a dog will settle down or even go to sleep before yo can over dose them. To be sure, consult a professional before you blame me for any advice I was given and have tried. : )