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Ali Al-Qhtani
The ABO antigens are terminal sugars found at the end of long sugar chains (oligosaccharides) that are attached to lipids on the red cell membrane. The expression of ABO antigens is controlled by 3 separate genetic loci:1)ABO gene located on chromosome 92)FUT1(H) gene on chromosome 193)FUT2(H) gene on chromosome 19( secretor gene)oThe expression of A or B antigens depend on H and Se genesAt least 2 genes, FUT1and FUT2oThe secretor population (80%), these antigens are found in soluble form in secretions and body fluids e.g. plasma, saliva.•They are responsible for production of H antigen •Both encode alpha 1,2 fucosyltransferase that catalyse transfer of fucoseto terminal galactose residue of the H precursor chain•FUT-1 is active in mesodermal derived tissues including hematopoietic tissues and is responsible for H expression on RBC•FUT2is responsible for the expression of H antigen on endodermaltissues including those responsible for secretion and hence the gene responsible for ABH secretion
Precursor chain of
sugars is formed most
frequently as either
Type 1 or Type 2
depending on the
linkage site between
the
N-acetylglucosamine
(G1cNAc) and
Galactose(Gal).
•Secretors are homozygous or heterozygous for the active allele (Se) ,non secretors are homozygous for the inactive allele (se).
-Type II found on RBC
Type I&II found in secretion
What else can I help you with?
A man with blood group a married with a woman blood group o what is the blood group?
Their children can have blood groups A or O.
If mother has blood group AB and her son has O blood group what will be the group of father?
O
What will offspring have if man has blood group A woman blood group O?
It can be A or O
Can o positive blood group marry o positive blood group?
no
Can a man with blood group o positive be father to a baby with blood group o?
Yes, a man with blood group O positive can be the father of a baby with blood group O. Blood group O is inherited when a child receives an O allele from both parents, so the father must have at least one O allele to pass it on to the child.
Your blood group is o positive and your girlfriend blood group also o positive?
what is a gf blood group? And what is the question?
Is it possible if mother with blood group O married to a father with blood group AB to have a child with blood group O?
No
What are the advantages of blood group o positive?
The advantage of the blood group O positive is that O positive blood can be given to any blood group. This is especially important when it comes to blood shortages.
WHAT could be your parents blood groups if Am of blood group A and your brother is of blood group O?
If you are blood group A and your brother is blood group O, your parents could have the following possible blood group combinations: one parent could be blood group A (genotype AA or AO) and the other could be blood group O (genotype OO). Alternatively, both parents could be blood group A (genotype AO). This combination allows for the inheritance of the O allele to produce a child with blood group O.
Is it blood group A blood groupB blood group AB or blood group O which is dominant?
dorminant
What blood group is used for a 0 blood group?
o
What is neymar blood group?
Neymar's Blood Group is O+
