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Yes, painkillers can be mixed with sleeping pills, however, mixing two downers together can produce other side effects such as nausea dizziness and heavy sedation. if painkillers arent enough to put you to sleep, try taking a benadryl or a swig of NyQuil. i have never tested prescription pain killers with prescription sleep aids.

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Wiki User

12y ago
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Wiki User

14y ago

In most cases no! It will synergize and cause the oxycodone and medication to make you stop breathing all together. Your respiratory system will be depressed severely and you may die. Check the name of your sleeping drug on this website to see if they do interact with each other. http://www.drugs.com/drug_interactions.php

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Wiki User

14y ago

Umm... it depends on several factors. How much you're taking, your tolerance to the drug, and what you're mixing the Oxycodone with. Please be more specific in your question so we can help you out. Thanks :)

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Wiki User

12y ago

Sure! Just like you can mix Acetone with Hydrogen Peroxide. You can mix practically anything with anything, but why would you want to? I'm sure it wouldn't do much harm to your body, as melatonin is a naturally-occuring chemical produced by the brain. It's production is triggered by darkness and quiet, as a sign of night time (which means time to go to bed).

It will make you sleepier, but the main concern would be how much you take. If you are taking a lot of Opiates without a tolerance (to get the Euphoria), than you are most likely "nodding out". This is when you "nod" in and out of consciousness briefly, regardless of your position, as you are overwhelmingly comfortable from the Opiates taking effect. The melatonin may prolong these nod-outs and can increase the risk of death by choking (swallowing your tongue), or simply not breathing enough because of the relaxation.

If you're going to do it, start with small amounts first. Then move up slowly depending on the result.

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Actavis

Lvl 2
4y ago

Hey no doctor here, but you can mint OxyContin with Zopiclone. you can with diazepam and these mad ones I use to get. But don't overtake what you have to man. I just hve lots of questions abouts zopiclone myself

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Wiki User

10y ago

Can you mix Zopiclone and Percocet

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Q: Can you take oxycodone and OTC sleeping meds together?
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