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Helium is an inert gas, so inhaling it should not cause any damage whatsoever as long as you also receive sufficient oxygen to survive (if you don't, then "death" probably counts as "lasting damage"). A mixture of helium and oxygen is often used by divers going far under the surface of the water, as helium is not very soluble in the blood and hence does not cause the "bends" as a nitrogen-oxygen mix can. Helium, however, contains no oxygen, so you can not breathe it alone indefinitely. Also, your brain might get confused because it "thinks" you inhaled, but you got no oxygen, and that is different than holding your breath.

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Q: If you inhaled helium would it cause any lasting damage?
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