No. The "Second City" term comes from the second-most theatrical city in the country, NYC being the first.
The two cities in Illinois that share a street with universities at each end are Chicago and Champaign. Specifically, the street is Illinois Route 45, also known as University Avenue, which runs from the University of Illinois at Urbana-Champaign to the University of Chicago in Chicago. This connection highlights the prominence of higher education in both cities.
The two cities that route 66 runs through are Chicago and L.A.
NY AND CHICAGO!
There are no other U.S. cities with the name Chicago. Chicago, Illinois is the only U.S. city with the name Chicago.
The 3 biggest cities in Illinois are Springfield,Chicago,and Peoria.
Chicago and Toronto
chicago, illinois hammond, indiana
Chicago and Los Angeles
los angeles and chicago
Chicago, IL and New Orleans, LA
Two: Los Angeles and New York City.
Minneapolis and St. Paul, MNMinneapolis and St. Paul.