yes
Amide on heating.
Acetanilide can also be synthesized by reacting aniline with acetic anhydride, instead of acetyl chloride. This is known as the Acetic Anhydride Method.
Ch3-c(=o)-nh2
No, acetanilide is not a narcotic. It is an organic compound that has been used historically for its analgesic and antipyretic properties, but it has largely been replaced by safer alternatives due to its potential toxicity.
The amide group on acetanilide is an ortho/para director, so a simple nitration should work: a mixture of sulfiric acid and nitric acid should be sufficient. Afterward, separation of the ortho and para compounds (by column chromatography, probably) would be necessary.
Acetanilide contains an amide functional group (CONH-) and an aromatic ring.
An acetanilide is an amide derived from acetic acid and aniline, once used as an analgesic and antipyretic.
Acetanilide is a neutral compound and will not react with litmus paper, which is typically used to test for acidic or basic conditions. Therefore, there will be no observable change in the color of litmus paper when it comes in contact with acetanilide.
the most suitable for recrystrallizing acetanilide is water..
Among the compounds listed, aniline is the most basic as it has a lone pair on the nitrogen atom that can readily accept a proton. Benzylamine and p-nitroaniline are less basic due to the presence of electron-withdrawing groups, while acetanilide has a resonance-stabilized amide group that reduces its basicity.
that the amide is a deprotonated form of ammonia.
The Acetanilide is a benzene with a acetamido group attached to it. The acetamido group is electron donating and therefore it directs other substituents to the ortho and para positions. The acetamido group is also a very large group and the ortho position is right besides the acetamido group. This creates steric hindrance from bromine from getting to the ortho position and therefore only para-bromoacetanilide or 4-bromoacetanilide is created mainly from a bromination of acetanilide.
Yes, acetanilide is likely to dissolve in hot heptane due to their similar polarities. Heptane is a nonpolar solvent which can dissolve nonpolar or slightly polar compounds like acetanilide. Heating the solvent can increase its ability to dissolve the compound.
Acetanilide is a neutral compound. It does not exhibit acidic or basic properties as it does not readily donate or accept protons in water.
Nitric acid and sulfuric acid are added to acetanilide to facilitate the nitration reaction. Nitric acid provides the nitronium ion needed for nitration, while sulfuric acid acts as a catalyst and helps in protonating the acetanilide molecule. This process allows for the substitution of a nitro group onto the acetanilide molecule.
Amide on heating.
Acetanilide is used instead of aniline in the synthesis of p-nitroaniline to control the selectivity of the reaction. Acetanilide is less reactive than aniline, making it easier to control the nitration process and avoid the formation of unwanted byproducts. Additionally, the acetanilide group can be easily removed after the nitration reaction to yield p-nitroaniline.