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Mixing these two stimulants which have similar actions will result in over-exertion, hypertension, and tachycardia. This can be dangerous to the circulatory system and can result in a heart attack. Furthermore, these two medications are extended release preparations of amphetamine and methylphenidate, they are meant to last one individual for the entirety of the day. Mixing them will result in over-stimulation lasting for ten or more hours. Short term warnings aside, it can lead to heart problems later in life. This is a dangerous combination and it is suggested that no individual should combine these two stimulants.
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