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Nicotine is a psychostimulant that is being researched for schizophrenia, ADHD, and Alzheimer's. Nicotine is also used in tobacco which provides the rewarding effects of smoking, and causes addiction.

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13y ago
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14y ago

Clinical trials are now underway on drugs that use nicotine -- which acts on the acetylcholine receptors in the brain -- to treat wounds, depression, schizophrenia, Alzheimer's disease, Tourette Syndrome, ADHD, anxiety, and other disorders. "Nicotine is highly stigmatized -- and for good reason, because the delivery system is so deadly," said Don deBethizy, CEO of biotech firm Targacept and formerly a researcher with R.J. Reynolds Tobacco Co. "But the drug itself and the research generated by studying its effects on the brain both show great promise for helping us improve our physical and mental health." The development of nicotine patches for smokers trying to quit, as well as studies showing that smokers seemed to be protected from certain diseases, helped spur research into therapeutic use of nicotine. Still, nicotine-based pharmaceuticals face a stigma given the drug's long association with smoking.

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Q: Is there any medical uses for Nicotine?
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