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Briefly:
1. Cells are exposed to parvovirus and take it up.
2. Some trigger causes parvovirus to release its genetic material.
3. Host cells begin to replicate the parvovirus; parvovirus is 100% dependent on its host for replication machinery.
4. Viral particles are released.
Specifically:
Canine parvovirus is a small non-encapsulated single-stranded DNA virus related to feline panleukopenia virus. It binds to the canine (and in some cases feline) transferrin receptor. It is probably taken up through clathrin-mediated endocytosis according to Parrish et al in J Virol 2004 Jul;78(13):6709-14. An as-yet unknown trigger causes the release of its ssDNA. The DNA then uses host ribosomes to synthesize its VP1 and VP2 (capsid) proteins as well as its NS1 and NS2 (for non-structural) proteins. Host DNA-dependent DNA polymerase replicates the genome. Packaging occurs, probably helped along by the non-structural proteins, followed by heavy-capsid release (heavy capsid means capside with DNA inside).
For binding, see http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17420467
For uptake see http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=15194745
Basically a PubMed search of Parrish CR[Author] will give you all the best articles on CPV-2 as it's called.
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Can a human catch parvovirus from a dog?
Canine Parvovirus is only specific to the dog. It cannot be transmitted to a human.
Are DHPP and DA2PP the same thing?
DHPP generally defends agains distemper, hepatitis, parainfluenza,and parvovirus and DA2PP generally defends against canine distemper, adenovirus type 2, parainfluenza, canine parvovirus, and canine coronavirus. No they ARE NOT the same :)
Can parvo kill humans?
There are strains of Parvovirus that can be harmful to humans. However, each type of Parvovirus is specific to one species, so Canine Parvovirus cannot hurt a human.
What disease appeared in 1978 that attacks the intestinal tract in dogs?
Canine parvovirus .
Feline panleukopenia is unrelated to canine parvovirus although both have what similar everyday name?
Distemper?
Can people get parvo from dogs?
No, it is not the same as human parvo.The human is the b-19 parvovirus.some animals parvovirus are..Canine parvovirusChicken parvovirusFeline panleukopenia virusFeline parvovirusaKilham rat virusLapine parvovirusMink enteritis virusMinute virus of miceMurine parvovirus 1Porcine parvovirusRaccoon parvovirusRT parvovirus
How do you get parvo out of your yard?
The short answer is that you don't - canine parvovirus is very hardy and can survive for years in the soil. This is why you should vaccinate your puppy per your veterinarian's recommendations.
What vaccines does the abbreviations DA2PPvL stand for?
Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine, Modified Live Virus-Leptospira Bacterin
Is avian flu DNA or RNA?
The virus has DNA as its genetic material. More interesting, the DNA is single-stranded. "Parvo" is short for "parvovirus" and usually "canine parvovirus type 2."
Can humans contract Mouse Parvovirus?
No, mouse parvovirus is specific to mice. Mouse parvovirus does not cause disease in mice, but can affect some types of research.
Does parvovirus attack connective tissue?
Parvovirus in humans affects the skin and possibly joints.
Can old dogs get parvovirus?
A dog of any age can contract parvovirus if it has not been vaccinated.
