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It takes 8 hours 25 minutes to drive the 499.2 miles from Orlando, FL to Myrtle Beach, South Carolina. Flights take from 3 hours 15 minutes to 10 hours 40 minutes depending on the number and duration of stops.

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9y ago
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13y ago
  1. Take US-501 NORTH to US-378 in Conway.
  2. Turn left onto US-378 WEST and take US-378 WEST to I-95 SOUTH to SAVANNAH.
  3. Take I-95 SOUTH through South Carolina and Georgia to I-4 WEST to ORLANDO at EXIT 260B in Florida
  4. Take I-4 WEST to ORLANDO.
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13y ago
  1. Take US-17 SOUTH to Charleston.
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11y ago

Google Maps estimates the driving time as 8 hours and 43 minutes.

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12y ago

It is 500.04 miles according to MapQuest.

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Wiki User

7y ago

Just about 500 miles

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Q: Miles from Myrtle Beach to Orlando Florida?
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