Persons who are resistant to HIV are missing an HIV coreceptor on the surface of their T4 cells Which step in the virus replication cycle is prevented?

Answer 1

First of all people who are missing an HIV co receptor on the CD4+ cells must have serious issues. Either of those co receptors (CCR5 or CXCR4) or chemokine receptors, meaning that chemokines bind to those receptors to tell them where to go during an infection. if either of those co-receptors are missing, their could be serious reprecussions

IF somebody is missing one of those co receptors, nothing in the virus replication cycle is prevented, the virus uses those receptors to bind to the cell, then open it up and enter. If one of those receptors is missing, it simply blocks one type of HIV virus from entering the cell, another one will just enter. IF both co receptors are missing, chances are that guy's prolly already dead anyways

Answer 2

The step in the virus replication cycle that is prevented is the binding and entry of the virus into the T4 cells. Without the HIV coreceptor, the virus cannot attach to and enter the cells, thus preventing the replication process from progressing.