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Both chicken hearts and mammalian hearts serve the primary function of pumping blood throughout the body, and both have four chambers—two atria and two ventricles, although the structure and arrangement can vary. A key difference lies in their physiology: chicken hearts are more efficient for their high metabolic demands during flight, while mammalian hearts are adapted for a wide range of activities, including sustained endurance. Additionally, chicken hearts have a more compact structure, while mammalian hearts exhibit a greater degree of specialization in their chambers and valves. Lastly, the regulation of heart rate and contraction can differ due to variations in hormonal and neural controls.

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