The talus bone or ankle bone is the second largest bone in the foot after the calcaneous or heel bone. The talus bone connects to the tibia and fibula bones in the lower leg. The talus bone is one of the bones in the human body that is most covered by articular cartilage on its surface area.
i think it will depend on what part of the body you are referring to, for example, the femur is the largest long bone, the pelvis is the largest flat bone, and the calcaneus is the largest in the tarsus. Hope this helps :)