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Blood group A individuals will have Anti-B antibodies.

Group A individuals make up 28% of the Asian population, 27% of the Black population, and 40% of the White population.

The genes for group A are on chromosone 9, and the gene product is N-Acetylgalactosaminyltransferase, which transfers N-Acetylgalactosamine to an oligosaccharide chain on the surface of the red blood cell.

80% of group A people have both branched and linear oligosaccharide chains. 20% of group A people are a subgroup called A2, and the oligosaccharide chains are linear only. It is possible for an A2 individual to make Anti-A antibodies. Several other rare sub-groups of A also exist.

Source: Basic & Applied Concepts of Immunohematology, Second Edition, by Kathy D Blaney and Paula r. Howard.

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