penicillin
it bind with sence rna and inhibit the process of tranlation mainly antisence rna is laboratory synthesis oligonucleotide 20-30 nucleotides
Messenger RNA molecules are fed through the ribosomes during protein synthesis.
There are three primary types of RNA involved in protein synthesis: messenger RNA, transfer RNA and ribosomal RNA. Whereas most types of RNA are the final products of their genes, messenger RNA (mRNA) is an intermediate in the information transfer process
Messenger RNA is first synthesized in to nucleus then is sent to either the rough Endoplasmic Reticulum or free floating ribosomes for protein synthesis.
penicillin
In prokaryotes tetracycline, chloremphenicol can inhibit protein synthesis. Puromycin is an antibiotic that inhibit both prokaryotic and eukaryotic protein synthesis. Each antibiotics has specific mode of action where it inhibits by binding, for example Chloremphenicol block the peptidyl transfer step.
it bind with sence rna and inhibit the process of tranlation mainly antisence rna is laboratory synthesis oligonucleotide 20-30 nucleotides
Generally not: antibiotics are essentially antibacterials, that is drugs counteracting bacterial infections like pneumonia, salmonella and the like. The specific mechanism of working of antibiotics depends on the specific drug under examination. Penicillin and its derivatives are bacterial killers: they enters into the bacteria membrane and inhibit basic bacteria life processes. A few of these processes are also related to bacteria proteins syntheses and, under this point of view, these class of antibiotics are also protein synthesis inhibitors. The important think to remember is that they inhibit, among other effects, the synthesis of bacterial proteins, not of the host (generally a human) protein syntheses. Other antibiotics inhibits bacteria multiplication by thwarting bacteria DNA splitting and replication. Also in this case, since many proteins are involved in the DNA replication process, bacteria proteins are involved, but the main antibiotics effect is to inhibit DNA replication.
Transcription is the biological term for RNA synthesis.
most of the antibiotics kill or inactivate bacteria by inhibitting the protein synthesis... protein synthesis consists of 'transcription' and 'translation'.. the translation process requiers mRNA and ribosomes.Human(eukaryotic) ribosome is different from bacterial(prokaryotic) ribosome... Antibiotics inhibit the protein synthesis by altering the ribosomal constitution.Since human ribosomes are different from bacterial ribosome,the substances which are harmful to bacterial ribosome doesn't harm human ribosomes.. Thus human cells are immune to antibiotics..
RNA polymerase
Ribosomes contain RNA and is involved in protein synthesis. Mitochondria and plastids also contain RNA.
Transcription is the synthesis of messenger RNA from DNA in the nucleus.
RNA is involved in the synthesis of proteins.
1- Cell Wall Synthesis Inhibitors:Bacteria contain peptidoglycan that is highly essential in maintaining the cell wall structure. Cell wall synthesis inhibitors such as beta-lactams, cephalosporins and glycopeptides block the ability of microorganisms to synthesize their cell wall by inhibiting the synthesis of peptidoglycan.2- Interfering with Protein Synthesis:These classes of antibiotics inhibit the protein synthesis machinery in the cell. Some examples include tetracyclines, chloramphenicol, aminoglycosides and macrolides.3- Cell Membrane Inhibitors:Antibiotics such as polymyxins disrupt the integrity and structure of cell membranes, thereby killing them. These set of antibiotics are mostly effective on gram negative bacteria because these are the bacteria that contain a definite cell membrane.4- Effect on Nucleic Acids:DNA and RNA are extremely essential nucleic acids present in every living cell. Antibiotics such as quinolones and rifamycins bind to the proteins that are required for the processing of DNA and RNA, thus blocking their synthesis and thereby affecting the growth of the cells.5- Competitive Inhibitors:Also referred to as anti-metabolites or growth factor analogs, these are antibiotics that competitively inhibit the important metabolic pathways occurring inside the bacterial cell. Important ones in this class are sulfonamides such as Gantrisin and Trimethoprim.
gentamicin