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Some of the more common side effects of pramipexole (Mirapexin) include:

  • Changes in appetite and weight
  • Dizziness, lightheadedness, or fainting, especially when standing up (orthostatic hypotension)
  • Drowsiness
  • Hallucinations (seeing, hearing, or feeling things that are not there)
  • Nausea
  • Insomnia
  • Twitching, twisting, or other unusual body movements
  • Unusual tiredness or weakness

Several unusual adverse effects of pramipexole (and related D3-preferring dopamine agonist medications such as ropinirole) may include compulsive gambling, hypersexuality, and overeating,even in patients without any prior history of these behaviours. Other compulsive behaviors, such as excessive shopping and even cross-dressing, have been reported. These side effects are thought to be linked to the D3 activity of pramipexole, as D3 receptors are heavily expressed in brain regions involved in mood, behavior, and reward. (Wikipedia)

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15y ago

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