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The Mexican War of Independence (1810-1821) qualifies as the main reason, as the trade route was controlled by the Spanish Crown. After the war, Acapulco was no longer a friendly port for Spanish galleons.
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When did Manila-Acapulco Galleon end?
Manila-Acapulco Galleon ended in 1815.
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Acapulco - TV series - ended on 1961-04-24.
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Manila Metrostars ended in 2000.
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Manila Beer Brewmasters ended in 1986.
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