The city half way between Boone, NC and Orlando, FL, depending on what route you take, could be Charleston, SC.
Baileyton, TN
Edinburgh, IN
The halfway point between Fort Meyers, Florida and Knoxville, TN falls in or around Tifton, Georgia.
Atlanta
Eufaula, AL
What is the halfway point between Knoxville, tn and Anderson, sc
knoxville,tenn
Gerardeau missouri
West Haven, North Carolina.
It's about 70 miles from Knoxville to Crossville, going via Interstate 40. The closest city to a halfway point along that route is Kingston, which is 36 miles from Knoxville and about 35.5 miles from Crossville.
Interstate 81, Harrisonburg, VA 22802
Columbia, Jamestown, and Somerset, KY, are all about halfway between Louisville, KY and Knoxville, TN.
The distance between Knoxville, TN and Atlanta, GA id approximately 155 miles. Halfway would be about 77.5 miles. The only town that is close to that would be Blairsville, GA and it is about 75 miles from Knoxville, Tn. These distances are straightline distances and not road miles.
Knoxville, Tennessee is about 35 miles short of the actual halfway point, but it would be an ideal selection if you intend to remain overnight or spend some time seeing the city.