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Most of the time, it means the medical condition, temporomandibular joint disorder. It causes a restriction in movement of the mouth, as well as pain. That is not slang. However, it may mean other things:

Tap my Jack: It means "text me."

Too much Johnson: Having a large penis or too much sex.

Too much jina: When a woman has pubic hair showing out of her clothes.

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Q: What does TMJ in urban slang mean?
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