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Complement is part of the innate immune system (one you are born with). It consists of small protein molecules that circulate in the blood stream.

Complement has three pathways, The classic pathway; The alternative pathway; and the lectin pathway.

In the classical pathway, complement is activated by triggers such as the binding of an antigen to an antibody. In the alternative pathway, Complement is part of the natural immune system and complement assist in the opsonization, or the marking of an antigen to be destroyed by a phagocyte. This like the antigen has been marked with black marker so that a killer cell (phagocyte-cell eater) can find it to eat it. Finally the lectin pathway, which is similar to the classical pathway in terms of structure but this pathway starts with lectin or ficolin binding to sugars. After activation complement can trigger any number of events such as opsonization, chemotaxis, inflammation, and lysis (breaking) of cells.

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