Pref means a prefix, so "tetrad prefix" might be "quad."
"Pref" in a crossword clue typically suggests an abbreviation. It could indicate that the answer is a prefix or that the solving of the clue requires an abbreviation for a word or concept.
The clue is related to the crossword title
prefix
stands for prefix
To get crossword puzzle answers you look at the numbered clues and find out what they mean and what matchs the clue then you put your answer to the clue in its numbered space
jib
The crossword clue for the Welsh rabbit is the hare.
The Clue in the Crossword Cipher was created in 1967.
In most crosswords, a gp in lowercase in a clue means group.
"clue echo" for crossword aficianados, wherein one clue is repeated later in the puzzle.
hug, cuddle
The ISBN of The Clue in the Crossword Cipher is 0-448-09544-0.
Had a hard time figuring this out. It means spew! It was a crossword puzzle clue.