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NPI is the National Provider Identification number, a relatively new US system for assigning each health care provider an identification number used to identify the provider to health insurers and other systems.
It's also possible that you mistook "NPI" for "NPO."
Which is:
NPO is a Latin term the means Nil Per Os. In the medical field, this term means that the patient is supposed to refrain from eating or drinking anything for a period of time specified by their doctor. This is many times implemented before certain medical tests need to be run or before a person is to undergoing surgery.
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