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What does uptake mean in a bone scan?

Updated: 5/21/2024
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12y ago

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The term uptake, when used in connection with the imaging method called a bone scan, refers to the amount of radioactive material that is taken in (taken up - uptake) by the bones to facilitate the imaging.

To image bones this way, a radioactive chemical that "looks" like stuff that bones want to facilitate their health is injected into a patient. The bones see this material and start to collect it, and they end up gathering about half of it up (ball park figure). This causes the bones to "glow" with the emissions of the decaying radioactive material used in the procedure. An imaging system with a camera sensitive to the gamma rays is used to "look" at the bones and an image results.

The uptake of the tracer will be determined by how fast the metabolism of the bone is working. Faster metabolism will mean more uptake. Cancer, infection and a few other things cause a lot of uptake, and that is what makes them visible. They stand out as "hot spots" on the image.

The body metabolizes and dumps the radioactive material through the kidneys and urinary tract. You don't get any more radiation than a conventional X-ray gives you - probably quite a bit less.

The tracer, commonly 99mTc-Medronate (MDP), is a phosphate-based compound with technetium hooked in so the material will "glow" in the gamma ray spectrum and can be seen with equipment set up to look for electromagnetic radiation in those energy ranges. The nuclear medicine technologist can probably answer more questions for you, as can your physician.

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1w ago

Uptake in a bone scan refers to the uptake of a radioactive tracer by bones, which helps detect areas of abnormal bone activity. Different uptake patterns can indicate various bone conditions such as fractures, infections, or tumors. Comparing uptake levels in different areas of the skeleton can help in diagnosing specific bone abnormalities.

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An abnormal gallium scan of the body may show increased uptake in areas of inflammation or infection, such as in cases of abscesses, lymphoma, or osteomyelitis. Absence of gallium uptake in normal areas can also indicate abnormalities such as tumors or infections. Interpretation of a gallium scan should be done by a trained healthcare professional in conjunction with other diagnostic tests for a comprehensive assessment.


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The processes of bone scan imagining and radiocarbon dating are what?

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Related questions

What does persistent diffuse uptake mean on a bone scan?

There is an increased level of metabolic activity of the bone throughout the body.


What does physiologic uptake mean in a bone scan?

There is metabolic activity in the bone at levels expected through normal (physiologic) processes.


What does physiological increased uptake mean in a bone scan?

Physiological increased uptake in a bone scan refers to the normal uptake of the radioactive tracer by certain structures in the body, such as the bones, liver, and spleen. This uptake is considered to be within the expected range and does not necessarily indicate any abnormality or disease. It is important for the interpreting physician to distinguish between physiological uptake and abnormal uptake associated with a pathology.


What is focal uptake on a bone scan?

There is a particular area of bone that is much more metabolically active than the bone in the rest of the body.


What does the medical abbreviation SUV mean?

Standardized Uptake Value (radionucleide uptake used in reading a PET scan)


What is a Radio Uptake Scan?

i assume you mean radionucleid uptake scan? this is a scan performed with radioisotopes to determine areas of under activity and can be used in many parts of the body including the thyroid kidneys and liver.


What does SUV mean on a PET scan?

Standardized Uptake Values which aids in assessing patient response to cancer therapy.


What does increased uptake mean in a bone scan?

Increased uptake seen in a Bone scan can mean many things:To name a few of the most popular causes:InfectionTraumaDegenerative ChangesCancerIncreased uptake is also known as a Hot Spot - This helps Doctors locate problematic areas for further investigation and specific imaging that best shows anatomical structures of the HOT SPOT. Correlation is made with imaging along with blood work, symptoms and history to reach a diagnosis or good reason that warrants further investigation for more sinister causes.Hopefully this helps!Sean DIncreased uptake seen in a Bone scan can mean many things:To name a few of the most popular causes:InfectionTraumaDegenerative ChangesCancerIncreased uptake is also known as a Hot Spot - This helps Doctors locate problematic areas for further investigation and specific imaging that best shows anatomical structures of the HOT SPOT. Correlation is made with imaging along with blood work, symptoms and history to reach a diagnosis or good reason that warrants further investigation for more sinister causes.Hopefully this helps!Sean D


What is increased uptake in medical terms?

Increased uptake in medical terms refers to an increase in the absorption or utilization of a substance by the body. This can refer to the uptake of nutrients, medications, or other substances that are essential for health and functioning.


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Can you have a pet scan and bone scan on same day?

Yes, but bone scan has to be completed first.


After having a thyroid scan with uptake places of inactivity are detected what does this mean?

Any thyroid issues can be found out through a blood test too.