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Distilled water causes cells to lyse, so injecting distilled water into a vein will cause some degree of hemolysis. Hemolysis is the rupture of red blood cells. A small amount of distilled water would quickly mix with the blood and would cause little to no noticeable damage. A large amount of distilled water would cause much more damage, not just limited to hemolysis. Among other things, large amounts of pure water introduced to the body would alter the electrolyte composition of blood, which could cause brain damage or cardiac arrest and death. This is why fluids are administered to patients as saline (which includes an appropriate amount of salt), and also why athletes prefer to drink fluids with electrolytes as opposed to pure water.

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