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From Wikipedia, the free encyclopedia
Presentation
Cytomegalovirus (CMV) is a DNA virus in the family Herpesviridae known for producing large cells with nuclear and cytoplasmic inclusions. Such inclusions are called an "owl's eye" effect.
While CMV is found in almost everyone, and is usually fought off by the immune system, for people who are immunocompromised, by diseases, transplants, or chemotherapy the virus is not adequately destroyed and can cause damage to the eye and the rest of the body. HIV positive persons are most at risk, especially when the CD4 cell count is low. CMV commonly becomes reactivated and can cause systemic infection in immunocompromised persons such as transplant patients or those infected by HIV.
It affects the eye in about 30% of the cases involving immunocompromised patients by causing damage to the retina. Symptoms can include blurred vision, eye pain, photophobia, redness, and blindness. It may affect just one eye at first, but then may spread to the other.
See retinal photograph of CMV retinitis for the appearance of CMV retinitis.
TreatmentActive Cytomegalovirus retinitis is treated by an uveitis and ocular immunology specialist.Because the virus is so threatening to vision, it is usually treated by a vitreo-retinal surgeon, by antivirals such as ganciclovir or foscarnet, which can be taken orally, intravenously, injected directly into the eye (intravitreal injection), or through an intravitreal implant.
Aug 1998: Fomivirsen is the first antisense drug approved by the FDA (brand name Vitravene) as an intraocular injection for the treatment of cytomegalovirus retinitis.
Risk factorsThe systemic use of corticosteroids has recently been implicated as elevating the risk of CMV in AIDS patients.
Wiki User
∙ 12y ago
Viral_TDM
Hello there!
CMV stands for cytomegalovirus which is a type of herpes virus that can cause an infection in humans.
Hope you found this helpful 😄
Flossie Kozey
Wiki User
∙ 13y agoIts a viral infection like the flu
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Can a positive CMV-IgG be a kidney donor?
i received a renal transplant from a sister that was cmv positve....i got cmv, but was fine after a week...
Can you get CMV if you had it once?
CMV infection can become dormant for a while and may reactivate at a later time.
What is a serology lab test cmv igm?
CMV IgM is a lab test that detects IgM for cytomegalovirus (CMV), usually in blood. IgM usually indicates a recent or current infection; in the case of CMV, it may also indicate reactivation of an old, latent infection.
What is the preparation for a CMV test?
The adult CMV antibody screening test requires 5 mL of blood.
Can CMV cause an early miscarriage?
Yes cmv is a major cause of miscarriage and their is no cure available for it at this time!
What is the differense between a CDL and CMV?
CDL stands for Commercial Drivers Licence. It's the licence you must hold to operate a CMV. CMV stands for Commercial Motor Vehicle, and is the vehicle itself.
How is cytomegalovirus diagnosed?
Past or recent infection with CMV can be identified by antibody tests and CMV can be grown from body fluids.
How many new cases of congenital CMV disease occur every year in the US?
About 40,000 babies are born in the U.S. each year with CMV. CMV is the second leading cause of mental retardation, after down's syndrome.
What are the dangers of CMV?
Consequences of a CMV infection can be devastating in a pregnant woman, a transplant patient, or a person with human immunodeficiency virus (HIV).
What is the prognosis for infants with CMV infection?
With treatment most infants with congenital CMV survive, although almost all suffer from its effects.
What evaluations are used to diagnose CMV or fifth disease?
Blood tests are used to diagnose maternal antibodies against CMV or fifth disease.
How many women are infected by CMV prior to pregnancy?
From 50-80% of childbearing-age women have been infected by CMV prior to pregnancy.
