What is CPK chemistry blood test?

Updated: 9/18/2023
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CPK is an enzyme called creatine kinase. It is mostly found in the heart, brain and muscle tissues. When there is trauma or damage to those tissues the enzyme is released into the bloodstream where it shows up as an elevated CPK on bloodwork. CPK is often elevated after a heavy workout or any type of crushing injury. The CPK is often elevated soon after a heart attack. Some muscle degenerating diseases also can be detected by a constantly high CPK level. It is up to your physician to determine the significance of the result. CPK can further be broken down into specific sub-enzymes called iso-enzymes. One is heart specific, one is muscle specific and so on. So if a CPK level is elevated and the cause is not known, testing for iso-enzymes can indicate what body tissue the CPK is coming from.

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Q: What is CPK chemistry blood test?
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What color test tube is Cpk?


Should you fast before a full blood chemistry test?

If you must test for cholesterol or glucose, you will. Otherwise, no.

What vacutainer would you use for a blood chemistry test?

A centrifuge tube would be useful, but a regular test tube will suffice.

What is a normal blood creatinine phophokinase level?

A normal creatine phosphokinase (CPK) level is anywhere from 10 to 120 micrograms per liter (mg/L). CPK is released when a muscle is damaged and can show whether a person has had a heart attack.

CPK isoenzymes test?

DefinitionThe CPK isoenzymes test measures the different forms of creatine phosphokinase (CPK) in the blood. CPK is an enzyme found mainly in the heart, brain, and skeletal muscle.See also: Creatine phosphokinase testAlternative NamesCreatine phosphokinase - isoenzymes; Creatine kinase - isoenzymes; CK - isoenzymesHow the test is performedBlood is typically drawn from a vein, usually from the inside of the elbow or the back of the hand. The site is cleaned with germ-killing medicine (antiseptic). The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.Next, the health care provider gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm.Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.In infants or young children, a sharp tool called a lancet may be used to puncture the skin and make it bleed. The blood collects into a small glass tube called a pipette, or onto a slide or test strip. A bandage may be placed over the area if there is any bleeding.If you are in the hospital, this test may be repeated over 2 or 3 days. A significant rise or fall in the total CPK or CPK isoenzymes can help your health care provider diagnosis certain conditions.How to prepare for the testUsually, no special preparation is necessary.Tell your doctor about all the medications you are taking. Certain medications can interfere with test results. Drugs that can increase CPK measurements include the following:Amphotericin BAmpicillinSome anestheticsAnticoagulantsAspirinClofibrateDexamethasoneFurosemideMorphineAlcoholCocaineHow the test will feelWhen the needle is inserted to draw blood, you may feel moderate pain, or only a prick or stinging sensation. Afterward, there may be some throbbing.Why the test is performedThis test is done if a CPK test reveals that your total CPK level is elevated. CPK isoenzyme testing can help pinpoint the exact soure of the damaged tissue.CPK is made of three slightly different substances:CPK-1 (also called CPK-BB) is found mostly in the brain and lungsCPK-2 (also called CPK-MB) is found mostly in the heartCPK-3 (also called CPK-MM) is found mostly in skeletal muscleWhat abnormal results meanHigher-than-normal CPK-1 levels:Because CPK-1 is found mostly in the brain and lungs, injury to either of these areas can increase CPK-1 levels. Increased CPK-1 levels may be due to:Brain cancerBrain injury(due to injury, stroke, or bleeding in the brain)Electroconvulsive therapyPulmonary infarctionSeizureHigher-than-normal CPK-2 levels:CPK-2 levels rise 3 - 6 hours after a heart attack. If there is no further heart muscle damage, the level peaks at 12 - 24 hours and returns to normal 12 - 48 hours after tissue death.Increased CPK-2 levels may also be due to:Electrical injuriesHeart defibrillation (purposeful shocking of the heart by medical personnel)Heart injury (for instance, from a car accident)Inflammation of the heart muscle usually due to a virus (myocarditis)Open heart surgeryCPK-2 levels do NOT usually rise with chest pain caused by angina, pulmonary embolism (blood clot in the lung), or congestive heart failure.Higher-than-normal CPK-3 levels are usually a sign of muscle injury or muscle stress and may be due to:Crush injuriesMuscle damage due to drugs or being immobile for a long time (rhabdomyolysis)Muscular dystrophyMyositis(skeletal muscle inflammation)Receiving many intramuscular injectionsRecent nerve and muscle function testing (electromyography)Recent seizuresRecent surgeryStrenuous exerciseSpecial considerationsFactors that can affect test results include cardiac catheterization, intramuscular injections, recent surgery, and vigorous and prolonged exercise or immobilization.Isoenzyme testing for specific conditions is about 90% accurate.ReferencesAnderson JL. ST segment elevation acute myocardial infarction and complications of myocardial infarction. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 72.Barohn RJ. Muscle diseases. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 447.

Related questions

What does cpk mean in a blood test?

creatine phosphate kinase. it increases in heart disease & muscular disease.

What is a good cpk blood count?


Do you need to fast for cpk blood tests?


What color test tube is Cpk?


What does BUN stand for in a Chemistry test?

Blood urea nitrogen.

Should you fast before a full blood chemistry test?

If you must test for cholesterol or glucose, you will. Otherwise, no.

What is the significance of a slightly elevated creatine kinase blood test presumed not cardiac related?

cpk enzymes are found in cardiac muscle, skeletal muscle and the brain, cpk will be elevated 10 to 25 times the normal level following a myocardial infarction, they will also be elevated after a trauma to skeletal muscle and in progressive muscular dystrophy, cpk can be elevated after strenuous exercise.

What does the medical abbreviation blood CPK level mean?

Creatine Phosphokinase

Which section of the clinical lab will perform pregnancy test on blood specimens?

chemistry is the answer

What is a normal CPK rate?

Creatinine-phosphate-kinase is an enzyme found in heart and muscle. Normal blood CPK range is 38-174 units/L

What cpk stands for in blood test?

what is cpk. How is it increased by crestor? what is crestor? CPK, also known as CK and Creatine phosphokinase, is more formally called Creatine Kinase. This is a test performed to determine whether or not the individual has had a heart attack. Higher levels of CK indicate injured muscles or heart cells. Very heavy exercise, excessive drinking, injury to person via car accident or fall or etc., and drugs that lower cholesterol can all increase the level of CK in the blood. CK levels can be increased by drugs such as Crestor because it damages muscle. Crestor is a cholesterol-lowering medication or statin.

Can you eat sugar free jello before blood test?

may I eat a sugar free jello during a fast before a blood chemistry test. Its a non glucose test also.