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What does the medical abbreviation GVHD mean?
Graft-versus-host-disease
When is Graft versus host disease most likely to occur?
A Graft versus host disease is most likely to occur or happen, when a tissue transplant does not take because the body fights the transplanted tissue. The recipient or host body rejects the tissue and attacks it.
Why did Susan Bucher die?
graft-versus-host disease and finding out her cancer had returned.
What induces a graft-versus-host reaction?
A graft versus host reaction is a product of stem cells being used to treat disease and not taking to each other. Even when identical siblings have contributed, this complication can happen.
What does blood transfusion graft-vs.-host disease affect?
Blood transfusion graft-vs.-host disease affects mostly the blood.
What illness can result in a Graft VS Host disease?
Graft-versus-host disease (GVHD) can occur after a bone marrow or stem cell transplant, where the transplanted donor cells attack the recipient's tissues. It is a potentially serious complication that can develop in various types of transplants, including those for leukemia, lymphoma, and other blood disorders.
What transplanted tissues can cause graft-vs.-host disease?
The only transplanted tissues that house enough immune cells to cause graft vs. host disease are the blood and the bone marrow.
What forms of graft-vs.-host disease are there?
Bone marrow graft-vs.-host disease comes in an acute and a chronic form. The acute form appears within two months of the transplant; the chronic form usually appears within three months.
What are the key differences between acute and chronic graft vs host disease?
Acute graft vs host disease occurs within the first 100 days after a transplant and affects the skin, liver, and gut. Chronic graft vs host disease develops later and can affect multiple organs, causing long-term complications.
What do Radiating blood products destroy?
T-lymphocytes to prevent development of graft versus host reactions.
How common is bone marrow graft-vs.-host disease?
The tissues most affected by bone marrow graft-vs.-host disease are the skin, the liver, and the intestines. One form or the other occurs in close to half of the patients
What are the risks of stem cell transplantations?
In addition to the risk of a life-threatening infection following a stem cell transplant, patients receiving stem cells from donors risk serious complications from graft-versus-host disease (GVHD).
