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A chronic disease in which it is believed that the immune system fails to recognize the cells that compose the bile ducts as part of the same body, and attempts to destroy them
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Icd-9 code for primary sclerosing cholangitis?
571.6
What does the disease primary sclerosing cholangitis damage?
The disease primary sclerosing cholangitis damages to a person's liver. Many people do not experience symptoms. It causes inflammation of the bile ducts both inside and outside the liver.
What are the condition that cholestyramine treat?
primary sclerosing cholangitis (progressive liver disease)
What caused Walter Payton's death?
Payton suffered from Primary sclerosing cholangitis.
Does autoimmune disease attack the bile ducts?
Primary sclerosing cholangitis is a typical example of an autoimmune disease involving the bile ducts
If part of the is liver removed does the rest rejuvenate?
I've had the largest lobe of my liver removed and have been told that you never grow your liver back but it does regenerate back to full working capacity. If you know someone that is having some of their liver removed be sure to ask if it's because of PSC (primary sclerosing cholangitis). I was never told and had this liver disease for 3 yrs before being told. To read more of this condition and treatments, read... http://www.mayoclinic.com/health/primary-sclerosing-cholangitis/DS00918
What killed Walter Payton?
Walter Payton died from complications stemming from Primary Sclerosis Cholangitis, or PSC, and bile duct cancer. At first diagnosis, Payton was considered eligible for a liver trans plant, but the cancer dashed this hope. PSC attacks the bile duct causing bile to back up in the liver, thus destroying it.
Sclerosing cholangitis?
DefinitionSclerosing cholangitis refers to swelling (inflammation), scarring, and destruction of the bile ducts inside and outside of the liver.Alternative NamesPrimary sclerosing cholangitis; PSCCauses, incidence, and risk factorsIn this condition, the bile ducts inside and outside the liver become narrowed and scarred.The cause is often unknown.The disease is often seen in patients who have:Inflammatory bowel disease (Crohn's disease and ulcerative colitis)SarcoidosisChronic pancreatitisMany autoimmune disordersGenetic factors may also be responsible. Sclerosing cholangitis occurs more often in men than women. This disorder is rare in children.Sclerosing cholangitis may also be caused by:CholedocholithiasisToxicity from chemicals, copper, bile acidsInfections in the liver, gallbladder, and bile ductsSymptomsThe first symptoms are usually fatigue, yellowing of the skin and eyes (jaundice), and itching. However, some people may have no symptoms.Other symptoms may include:Loss of appetite and weight lossEnlarged liverEnlarged spleenRepeat episodes of cholangitisSigns and testsSome people do not have symptoms, but blood work reveals they have abnormal liver function. The doctor will rule out diseases that cause similar problems. For example, you will be checked for stones in the gallbladder or biliary tract.Tests that show cholangitis include:Abdominal CT scanAbdominal ultrasoundEndoscopic retrograde cholangiopancreatography (ERCP)Liver biopsyMagnetic resonance cholangiopancreatography (MRCP)Percutaneous transhepatic cholangiogram (PTC)Blood tests include:Elevated liver enzymes (liver function tests)TreatmentMedications that may be used include:CholestyramineUrsodeoxycholic acid (ursodiol)Fat-soluble vitamins (D, E, A, K)Antibiotics for infections in the bile ductsMedications that quiet the immune system (prednisone, azathioprine, cyclosporine, methotrexate)Surgical procedures:Inserting a long, thin tube with a balloon at the end to open up narrowing (endoscopic balloon dilation of strictures)Placement of a drain or tube for major narrowing (strictures) of biliary ductsProctocolectomy(for those who have both ulcerative colitis and sclerosing cholangitis)Liver transplantExpectations (prognosis)How well patients do varies. The disease tends to get worse over time and most patients develop:Biliary cirrhosisLiver failurePersistent jaundiceSome patients develop infections of the bile ducts that keep returning. Patients may have chronic liver disease that gets worse, with ascites and varices.People with this condition have an increased risk of developing cancer of the bile ducts (cholangiocarcinoma). They should be checked on a regular basis (usually each year) with liver scans and blood tests.ComplicationsBleeding esophageal varicesCancer in the bile ducts (cholangiocarcinoma)Cirrhosis and liver failureInfection of the biliary system (cholangitis)Narrowing of the bile ducts (strictures)Vitamin deficienciesReferencesGordon FD. Primary sclerosing cholangitis. Surg Clin North Am. 2008;88:1385-1407.Tung BY, Kowdley KV. Sclerosing cholangitis and recurrent pyogenic cholangitis. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger & Fordtran's Gastrointestinal and Liver Disease. 8th ed. Philadelphia, Pa: Saunders Elsevier;2006:chap 65.
Is cholangitis caused by tumors?
Tumors can block the bile duct and also cause cholangitis
Where might one learn more information about cholangitis symptoms?
Cholangitis is an infection on the bile duct. Symptoms of cholangitis can be found online at Mayo Clinic, Right Diagnosis, Medicine Net, and Symptoms Diagnosis Book.
What is cholangitis?
Inflammation of the bile duct.
What is needed for cholangitis?
The two things that are needed for cholangitis to occur are: 1) obstruction to bile flow, and 2) presence of bacteria within the bile ducts
