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Hypertensive EmergenciesA hypertensive emergency is a condition in which elevated blood pressure results in target organ damage. The systems primarily involved include the central nervous system, the cardiovascular system, and the renal system. Malignant hypertension and accelerated hypertension are both hypertensive emergencies, with similar outcomes and therapies. In order to diagnose malignant hypertension, papilledema (as seen in the image below) must be present.[1]

Papilledema. Note the swelling of the optic disc, with blurred margins.

Up to 1% of patients with essential hypertension develop malignant hypertension, but the reason some patients develop malignant hypertension whereas others do not is unknown. The characteristic vascular lesion is fibrinoid necrosis of arterioles and small arteries, which causes the clinical manifestations of end-organ damage. Red blood cells are damaged as they flow through vessels obstructed by fibrin deposition, resulting in microangiopathic hemolytic anemia.

Another pathologic process is the dilatation of cerebral arteries following a breakthrough of the normal autoregulation of cerebral blood flow. Under normal conditions, cerebral blood flow is kept constant by cerebral vasoconstriction in response to increases in blood pressure. In patients without hypertension, flow is kept constant over a mean pressure of 60-120 mm Hg. In patients with hypertension, flow is constant over a mean pressure of 110-180 mm Hg because of arteriolar thickening. When blood pressure is raised above the upper limit of autoregulation, arterioles dilate. This results in hyperperfusion and cerebral edema, which cause the clinical manifestations of hypertensive encephalopathy.

Other causes of malignant hypertension include any form of secondary hypertension; complications of pregnancy; use of cocaine, monoamine oxidase inhibitors (MAOIs), or oral contraceptives; and the withdrawal of alcohol, beta-blockers, or alpha-stimulants. Renal artery stenosis, pheochromocytoma (most pheochromocytomas can be localized using computed tomography (CT) scanning of the adrenals), aortic coarctation, and hyperaldosteronism are also secondary causes of hypertension. In addition, both hyperthyroidism and hypothyroidism can cause hypertension.

The following conditions should also be considered when making the diagnosis: stroke, intracranial mass, head injury, epilepsy or postictal state, connective-tissue disease (especially lupus with cerebral vasculitis), drug overdose or withdrawal, cocaine or amphetamine ingestion, acute anxiety, and thrombotic thrombocytopenic purpura.[2]

For more information, see Hypertension.

Accelerated hypertension and hypertensive urgencyAccelerated hypertension is defined as a recent significant increase over baseline blood pressure that is associated with target organ damage. This is usually seen as vascular damage on funduscopic examination, such as flame-shaped hemorrhages or soft exudates, but without papilledema.

Hypertensive urgency must be distinguished from hypertensive emergency. Urgency is defined as severely elevated blood pressure (ie, systolic >220 mm Hg or diastolic >120 mm Hg) with no evidence of target organ damage.

Hypertensive emergencies require immediate therapy to decrease blood pressure within minutes to hours.[3] In contrast, no evidence suggests a benefit from rapidly reducing blood pressure in patients with hypertensive urgency. In fact, such aggressive therapy may harm the patient, resulting in cardiac, renal, or cerebral hypoperfusion. This article discusses hypertensive emergency, but therapy for hypertensive urgency is discussed briefly.

Patient educationPatients must be taught an appropriate diet for long-term management, and upon discharge, patients should not only know the signs and symptoms that should prompt immediate notification of a physician but also know the proper dosing and adverse effects of their medications.
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How to Treat Malignant Hypertension

Malignant hypertension is characterized by extremely high blood pressure. Considered to be a medical emergency requiring a trip to the emergency room, symptoms may include headache, chest pain, cough and shortness of breath, blurred vision, seizure or numbness in the face, arms or legs. Physical examination may reveal retinal bleeding or swelling of the optic nerve. Kidney failure, permanent blindness or brain damage can develop as possible complications. While a person with this condition may be prescribed multiple medications, diet, exercise and lifestyle changes are essential in controlling and managing the hypertension.

Instructions

1.
  • 1

Limit grains and refined sugar in your diet. Lower insulin levels can help bring high blood pressure under control. Get adequate vitamin D, as a deficiency of this vitamin has been linked to insulin resistance, which is known to elevate blood pressure.

  • 2

Make exercise a priority once severe high blood pressure has been controlled. Talk to your doctor first about what types of exercise might best fit your needs. In most cases, a routine that rotates different kinds of exercise is the most effective. Focus on aerobic exercise some days, strength training on others, and incorporate stretching and flexibility exercises into your workout.

  • 3

Quit smoking. Smoking is one of the most common risk factors associated with malignant hypertension. Smoking damages the walls of blood vessels, increasing the risk for cardiovascular disease. The nicotine in tobacco products narrows the blood vessels, making it more difficult for blood to flow through. With each cigarette you smoke, your blood pressure rises. For people who already have high blood pressure, smoking accelerates the onset of malignant hypertension.

  • 4

Reduce anxiety and stress that cause you to overeat or drink alcohol, habits that can contribute to high blood pressure. One response to stress is constriction of blood vessels, causing blood pressure to rise. Previous studies conducted by researchers at the Harvard Medical School suggest that stress stimulates the production of epinephrine, boosting heart rate and narrowing blood vessels.

  • 5

Take your medications on schedule and as directed by your physician. Some of the medications commonly used to treat malignant hypertension include ACE inhibitors such as enalapril; vasodilators like hydralazine; a beta-blocker including labetalol; or a calcium channel blocker such as nicardipine. Most antihypertensive medications work by relaxing blood vessels, reducing the heart's workload. Try not to miss any doses, and do not discontinue medication without discussing with your doctor.

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As a student of psychology, design a psychology model for a student suffering from essential hypertension

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Q: What is adesign for psychological model for patient suffering from hypertension?
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Design a psychological model of treatment of a patient suffering from malignant hypertension?

Psychological treatment for a patient with malignant hypertension would typically involve stress management techniques, cognitive-behavioral therapy to address underlying psychological stressors contributing to hypertension, and lifestyle modifications like mindfulness practices and relaxation exercises. It's important to work collaboratively with medical professionals to ensure a holistic and coordinated approach to treatment. Regular monitoring and adjustment of the treatment plan based on the patient's progress and medical condition is crucial for long-term management of malignant hypertension.


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