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What is a bioisosterism?

Updated: 4/28/2022

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A bioisosterism is a relationship between bioisosteres, substituents or groups with similar physical or chemical properties that impart similar biological properties to a chemical compound.

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∙ 7y ago

A bioisostere is a compound derived from another by the replacement of a group of atoms by another broadly similar group, for example, the replacement of a methyl by an ethyl group.

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