vasodialation
Basophils and mast cells.
They are released by basophils and mast cells in nearby connective tissue.
Histamine.
E. histamine
Mast cells secrete histamine and heparin.
The parietal cell in the stomach secrets gastric acid, which is hydrochloric acid (HCl). The Secretion of HCl by the parietal cell is stimulated by receptors for acetylcholine (muscarinic), histamine, and gastrin. The enterochromaffin cells (ECL) also have gastrin receptors and muscarinic receptors. ECL cells release histamine which reacts with H2 receptors (histamine 2 receptors) on parietal cells. Somatostatin is released by delta cells and decreases histamine release by ECL cells.
Mast cells and basophils produce the histamine, which antihistamines block. The cytoplasm of a mast cell is filled with granules containing histamine and heparin. Histamine, released after injury or infection, stimulates local inflamation. People often take antihistamines to reduce cold symptoms. Basophils, blood cells that enter damaged tissues and enhance the inflammation process, also contain granules of histamine and haparin.
Eusonophils and Basophils produce histamine.Also mast cells produce histamine.
There are many, many substances released when tissues are injured, but one of the interesting ones would be prostaglandins. Some other substances of interest that are released would be histamine, antibodies, clotting factors, and a host of others.
mast cells
Mast cells.
Histamine is released by basophils and mast cells in near by connective tissue which is an immune response to foreign pathogens.