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Chromosome 22 contains about 693 genes. Some are:

  • gene to produce immunoglobulin
  • gene to make neurofilaments
  • gene for light chains of antibodies

Damaged genes can cause:

  • Schizophrenia
  • bilateral acoustic neuroma (hearing loss)
  • 22q13 deletion syndrome (autism)
  • Breast cancer
  • amyotrophic lateral sclerosis (ALS)
  • neurofibromatosis
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Q: What is chromosome 22 responsible for?
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What gene is responsible for CMT1A?

It is caused by a mutation in a gene called peripheral myelin protein 22 (PMP22) located on chromosome 17.


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For the development of male offspring.


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What cell type could have 22 chromosomes and a Y chromosome?

The cell type that has 22 autosomes and an X sex chromosome is a gamete, such as an egg or sperm cell.


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Why is a human cell containing 22 autosomes and a y chromosome a sperm?

Human somatic (body) cells contain two sets of 23 chromosomes. Human gametes (sperm and egg cells) contain one set of 23 chromomes -- 22 autosomes and 1 sex chromosome. Only a sperm cell can carry a y chromosome. A sperm cell can also carry an x chromosome. The ovum can carry only an x chromosome, never a y chromosome. So a cell containing 22 autosomes and a y chromosome must be a sperm cell.