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Cytochrome c, or cyt c (horse heart: PDB 1HRC) is a small heme protein found loosely associated with the inner membrane of the mitochondrion. It is a soluble protein, unlike other cytochromes, and is an essential component of the electron transfer chain. It is capable of undergoing oxidation and reduction, but does not bind oxygen. It transfers electrons between Complexes III and IV. http://en.wikipedia.org/wiki/Cytochrome_c
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Does halothane induce cytochrome p450?
Yes. There is scientific evidence to indicate that Halothane is able to induce cytochrome P450. P450 in turn anaerobically reduces halothane to potentially toxic metabolic compounds that cause liver damage
How many cytochrome P450 are there in the body?
There are over 50 different cytochrome P450 enzymes in the human body, each with specific roles in metabolizing various substances including drugs, toxins, and endogenous compounds.
What Enzymes oxidize cell substances?
Enzymes like catalase, cytochrome P450, and alcohol dehydrogenase are involved in oxidizing cell substances. Catalase breaks down hydrogen peroxide, cytochrome P450 is involved in drug metabolism, and alcohol dehydrogenase metabolizes ethanol.
What is the clinical importance of cytochrome P450?
The human cytochrome P450 comprises 57 genes. These genes code for enzymes that can have a role in: metabolism of drugs, foreign chemicals, cholesterol metabolism and more. P450 was once thought to be mainly a hepatic drug detoxication system, its now believed to include a myriad of enzymic reactions implicated in important life processes.
Where is ginkgo biloba metabolized?
Ginkgo biloba is primarily metabolized in the liver, mainly by the cytochrome P450 enzymes. It undergoes extensive metabolism before being eliminated from the body.
Which of the following drugs inhibits the cytochrome P450 system?
Cimetidine
How does diazepam undergo phase 1 metabolism?
Cytochrome P450 allows phenytoin to undergo aromatic hydroxylation to turn into phenol.
Does halothane induce cytochrome p450?
Yes. There is scientific evidence to indicate that Halothane is able to induce cytochrome P450. P450 in turn anaerobically reduces halothane to potentially toxic metabolic compounds that cause liver damage
How many cytochrome P450 are there in the body?
There are over 50 different cytochrome P450 enzymes in the human body, each with specific roles in metabolizing various substances including drugs, toxins, and endogenous compounds.
What Enzymes oxidize cell substances?
Enzymes like catalase, cytochrome P450, and alcohol dehydrogenase are involved in oxidizing cell substances. Catalase breaks down hydrogen peroxide, cytochrome P450 is involved in drug metabolism, and alcohol dehydrogenase metabolizes ethanol.
What is the clinical importance of cytochrome P450?
The human cytochrome P450 comprises 57 genes. These genes code for enzymes that can have a role in: metabolism of drugs, foreign chemicals, cholesterol metabolism and more. P450 was once thought to be mainly a hepatic drug detoxication system, its now believed to include a myriad of enzymic reactions implicated in important life processes.
How does amphetamine undergo phase 1 metabolism?
Cytochrome P450 allows amphetamine to undergo oxidative deamination.
What has the author Karen Grierson written?
Karen Grierson has written: 'Role of the inducible cytochrome P450 isoenzymes in the metabolism of melatonin'
What has the author Kathryn Elizabeth Brocken written?
Kathryn Elizabeth Brocken has written: 'Cytochrome P450 isoenzyme activities in dog'
How does phenobarbital undergo phase 1 metabolism?
Cytochrome P450 allows phenobarbitual to undergo aliphatic hydroxylation. It then turns into an alcohol.
What has the author Thuong Hoang written?
Thuong Hoang has written: 'Expression of cytochrome P450 1B1 in preneoplastic conditions of the colon and cervix'
How does codeine undergo phase 1 metabolism?
Cytochrome P450 and CYP2D6 allow codeine to undergo O-demethylation to form morphine.
