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To my knowledge, mixing tests are used with some types of acquired hemophilia to determine the source of the hemophilia. In the test, I believe they mix two separate samples of plasma together. One sample being from the affected individual who has acquired hemophilia, one from a normal source without the acquired hemophilia.

If the ability of the blood to coagulate is decreased, this would indicate that the source of the acquired hemophilia was in the blood itself (some anticoagulant).

If the blood, once mixed retained normal clotting, this would indicate a problem with the actual production of the needed clot forming components.

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Q: What is mixing test in Hemophilia?
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