sicke cell disease
Substitution.
Substitution
Mutation occurs where one DNA nucleotide base is changed in the process of DNA replication. These mutations may or may not cause genetic disorders or other observable changes in the organism, but they play a huge role in evolution, cancer, and immune system development.
When a nitrogen base is substituted for a different one so it may code for a different amino acid. Sometimes substitution still codes for a same amino acid, in which case it becomes a silent mutation, but in other times it may alter the protein entirely.
frameshift- deletion and insertion point mutation- sustitution
Substitution.
Substitution
frameshift mutation
Mutation occurs where one DNA nucleotide base is changed in the process of DNA replication. These mutations may or may not cause genetic disorders or other observable changes in the organism, but they play a huge role in evolution, cancer, and immune system development.
When a nitrogen base is substituted for a different one so it may code for a different amino acid. Sometimes substitution still codes for a same amino acid, in which case it becomes a silent mutation, but in other times it may alter the protein entirely.
frameshift- deletion and insertion point mutation- sustitution
why is frameshift mutation more damanging than a substitution
The substitution of one triplet code in the DNA that codes for an mRNA that codes for an amino acid that makes up a protein. Sickle cell trait is an example of this. One amino acid substitution in a B chain of hemoglobin and you have an allele that will code for sickle cell trait.
Insertion
substitution
Missense
The three types of Mutations are: Substitution Deletion Addition For example: Mutation stand to compare back to: ATG CAT AGG Mutation#1: ATT CAT AGG It is Substitution in this strand because the "G" was changed to a "T." Mutation#2: ATG ATA GG It is Deletion in this strand because the "A" was deleted. Mutation#3: ATG CAT TAGG It is Addition in this strand because another "G" was added to the end of the strand.