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add. The chemical nature of an element, and its interaction with other elements to form compounds, is controlled by the number of electrons. All isotopes of Oxygen have 8 electrons and 8 protons, but variable number of neutrons. In the case of O18, it has ten neutrons.

This is a valuable isotope, for the O16:O18 ratio is responsive to the ambient temperature. And thus we may infer ancient climates from this ratio in shells and ice cores.

O18 may also be used in the production of positrons for medical use.

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