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Pure chemistry is a way to express that a certain process or result was not achieved by any other means. For example distilling is physical process. "Refining" could be a process chemical, physical or both. Sometimes is the term "pure chemistry" used for materials synthetically produced or engineered.

Ethylvaniline is produced only synthetically from lignine (from wood) and the resulting flavour of pure ethylvaniline is to some people irritating, because it lacks the various by-products and impurities that the natural vanilla flavor contains. Such a person could say about the ethylvaniline flavoring that it is "pure chemistry", lacking the natural substance.

Some cheap carbonated bottled waters are best described with this term because they only contain water, carbon dioxide, Aspartame, citric acid, coloring. Naturally occurring substances never come in their pure form, but as a wide spectrum of chemical compounds of various concentrations.

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