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The fastest route to drive from Orlando Florida to Jacksonville Florida is on a US Interstate highway. In this case that highway is Rt. 95.
The shortest distance is via Fort Worth and Amarillo using Interstate 45 and US 287, however the fastest route uses Interstate 35 North and Interstate 70 West.
I-95 south to Jacksonville I-75 south to Tampa
The fastest and shortest way would be to take Interstate 55 North, then Interstate 57 North.
It appears that the Shortest route I can find is from Jacksonville Beach, FL to San Diego, CA, at a distance of 2,109 miles according to Google Maps.
Yes, I-26 provides the shortest and fastest driving route.
Interstate 89, Interstate 91, Interstate 93, US Route 7, US Route 2, US Route 4, US Route 302, US Route 5, VT Route 100, and VT Route 22A
The shortest and fastest highway route from New York City to Miami, Florida will be along Interstate 95 South all the way. The approximate distance from New York City to Miami along I-95 is 1,276-miles.
Google Earth cites the shortest route as 346 miles... with a journey time of 4 hours 55 minutes.
It looks as if the shortest route, as far as driving time is concerned, is to take interstate 80 east to interstate 65 south/70 east toward Columbus. Then you take exit 4A from 70 east to get to 3rd street in downtown Columbus
Interstate 89, Interstate 91, Interstate 93, US Route 7, US Route 2, US Route 4, US Route 302, US Route 5, VT Route 100, and VT Route 22A
The shortest route is on I-90 W.