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red pulp is a blood containing region which lie in the spleen, in which open circulation takes place. the open circulation is a pathway taken by the blood in the spleen to flow from the central artery in the white pulp( which will be explained later) through the red pulp and back again to circulatory vessel (vein). blood flow in the open circulation will be exposed to lymphocyte and macro phages in the billroth's cord before it enters splenic sinusoids. this will give better exposure for the blood against any antigen that might present.

while the white pulp is the light stained region in the spleen. it consists of central arteries( splenic.a - trabecular.a- central.a), which been sorrounded by periarterial lymphatic sheath( occupied by T lymph). the latter will be sorrounded by lympoid nodules called malphigian corpuscle( occupied by b lymph).

between the white and red pulp, there is a marginal zone. this site is the site where highest accumulation of lymphocyte and macrophages. there are also lymphocyte from the red pulp an gather here. it can be said that marginal zone acts as initial immune reaction region.

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12y ago
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Q: What is the Difference between white pulp and red pulp?
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