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Hydrocodone and codeine are NOT the same chemical compound; they're two different drugs.

Codeine is the 3-methylether of morphine. It's almost inactive on it's own, and needs to be converted into morphine via the enzyme CYP2D6 in the liver to cause opioid effects, hence it's a prodrug. The Schedule 4 version of Codeine (syrups, mixed as analgesic with other drugs like Tylenol) is still a pretty weak opioid painkiller and severe pain will typically require something stronger. The Schedule 2 version is an extremely strong opiate, but isn't typically prescribed to most patients; the Schedule 4 version is.

Hydrocodone's chemical structure is similar to codeine's but not the same. It's a great deal stronger than codeine and is hence more effective in reducing severe pain. Hydrocodone also has less severe side effects, such as itching and nausea, than codeine.

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Q: What is the difference between hydrocodone and codeine?
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Related Questions

What is the difference between hydrocodone and cod?

Hydrocodone and codeine are both prescription pain relievers. The difference between them is that hydrocodone is made from codeine, and is often combined with Tylenol. Meanwhile, codeine is made from morphine, and is stronger.


What is the difference between hydrocodone and hydrocodine?

There is not a difference in these two medications. They are exactly the same as they are both an analgesic and derives from codeine.


What is the difference between hydrocodone APAP 5mg500mg And hydrocodone APAP 10mg325mg?

5mg 500mg has 5mgs of codeine and 500mgs of Tylenol 10mg 325mg has 10mgs of codeine and 325mgs of tyelenol so basically your getting more codeine less Tylenol and vice versa


What is the difference between hydrocodone and hydromorphone?

Hydrocodone is a derivative of codeine which breaks down into morphine once it reaches the liver and is a synthesized opiate. Hydromorphone is a derivative of morphine.


Can you take Vicodin if allergic to codeine?

no, vicodin is hydrocodone, which is a codeine.


Is there codeine in hydrocodone?

No. Hydrocodone is its own opiate molecule, distinct from codeine.


What is the difference in hydrocodone apap and hydrocodone bitartrate?

what is the difference between Hydrocodone Bitartrate and Hydrocodone/acetaminophen


Which is safer hydrocodone or codeine sulfate?

Hydrocodone is an extract of codeine, so they are the same. You just have to take more hydrocodone


What is the difference between Hydrocodone and Hydrocodone Bitartrate?

Answer#1There is no difference.


Does Hydrocodone have Codeine in it?

No. Hydrocodone and Codeine are two separate drugs with different chemical makeups.


What is the difference between Dilaudid and norco?

ones hydromorphone and one is codeine based Actually neither is codeine based. Norco is hydrocodone and tylenol. It is the same as lortab or vicodin only with less tylenol. Hydrocodone is metabolized or broken down in the body into hydromorphone metabolites.


What is the difference between codine and hydrocodone?

*codeine* is a naturally occurring opiate alkaloid found in poppies, hydrocodone is a semi-synthetic opioid sold most commonly under the brand name Percocet


Are Vicodin and Codeine related?

The opioid analgesic Hydrocodone is present in Vicodin and that Hydrocodone is related to Codeine.


Is codeine stronger than hydrocodone?

If perscribed liquid Codeine, Codeine. Other than that hydrocodone is a bit stronger pill form.


Does hydrocodone contain codine?

no, hydrocodone does not contain *codeine


What is the difference with codeine phosphate and dihydrocodeine?

What is the difference between Codeine Phosphate & Dihydrocodeine?


What drug is the strongest hydrocodone or codeine?

Hydrocodone is stronger. In Tylenol #4 tablet, the 60 mg of codeine is about as effective as 10 mg of hydrocodone.


What is the chemical difference between hydrocodone and oxycodone?

please tell me the chemical difference between hydrocodone and oxycodone


Does hydroco have codeine?

if by hydroco you mean hydrocodone, then yes and no. Hydrocodone is a semi-synthetic opioid that is made FROM codeine. Hydrocodone does not metabolize into codeine frome what ive read. If you are allergic to codeine then you will probably be allergic to hydrocodone too. If youre trying to pass a UA then you should be ok as most urine tests that test for opiates only test for morphine and codeine; neither of which are metabolites of hydrocodone. If you're looking to treat pain, then keep in mind that hydrocodone is stronger than codeine.


What is the difference between oxycodone and vicotine?

Vicodin* is a brand name for hydrocodone, which is different than oxycodone. The two are quite similar as they are both derived from codeine. Oxycodone however is about 50% stronger than hydrocodone (vicodin).


If your allergic to codiene can you take hydrocodone?

No hydrocodone is an extract of codeine


Can I take vicodene if allergice to codeine?

Nope. vicodin contains hydrocodone wich is an extract of codeine


Can you take hydrocodone if you are allergic to codeine?

Yes. Hydrocodone is a synthetic derivative of codeine. It does not contain the actual substance. I would also add that in my experience, the nausea seen with use of codeine is rarely seen with hydrocodone.


Ats the difference between Vicodin and hydrocodone?

Vicodin is hydrocodone.


If you were drug tested could you tell between codeine and hydrocodone?

yes, both are opiates