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Hydrocodone and codeine are NOT the same chemical compound; they're two different drugs.

Codeine is the 3-methylether of morphine. It's almost inactive on it's own, and needs to be converted into morphine via the enzyme CYP2D6 in the liver to cause opioid effects, hence it's a prodrug. The Schedule 4 version of Codeine (syrups, mixed as analgesic with other drugs like Tylenol) is still a pretty weak opioid painkiller and severe pain will typically require something stronger. The Schedule 2 version is an extremely strong opiate, but isn't typically prescribed to most patients; the Schedule 4 version is.

Hydrocodone's chemical structure is similar to codeine's but not the same. It's a great deal stronger than codeine and is hence more effective in reducing severe pain. Hydrocodone also has less severe side effects, such as itching and nausea, than codeine.

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2011-09-15 05:48:46
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Q: What is the difference between hydrocodone and codeine?
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What is the difference between hydrocodone and cod?

Hydrocodone and codeine are both prescription pain relievers. The difference between them is that hydrocodone is made from codeine, and is often combined with Tylenol. Meanwhile, codeine is made from morphine, and is stronger.


What is the difference between hydrocodone and hydrocodine?

There is not a difference in these two medications. They are exactly the same as they are both an analgesic and derives from codeine.


What is the difference between hydrocodone APAP 5mg500mg And hydrocodone APAP 10mg325mg?

5mg 500mg has 5mgs of codeine and 500mgs of Tylenol 10mg 325mg has 10mgs of codeine and 325mgs of tyelenol so basically your getting more codeine less Tylenol and vice versa


Can you take Vicodin if allergic to codeine?

no, vicodin is hydrocodone, which is a codeine.


Is there codeine in hydrocodone?

No. Hydrocodone is its own opiate molecule, distinct from codeine.


What is the difference between hydrocodone and hydrocodone?

Answer#1There is no difference.


What is the difference in hydrocodone apap and hydrocodone bitartrate?

what is the difference between Hydrocodone Bitartrate and Hydrocodone/acetaminophen


What is the difference between Hydrocodone and Hydrocodone Bitartrate?

Answer#1There is no difference.


Which is safer hydrocodone or codeine sulfate?

Hydrocodone is an extract of codeine, so they are the same. You just have to take more hydrocodone


What is the difference between Dilaudid and norco?

ones hydromorphone and one is codeine based Actually neither is codeine based. Norco is hydrocodone and tylenol. It is the same as lortab or vicodin only with less tylenol. Hydrocodone is metabolized or broken down in the body into hydromorphone metabolites.


Does codeine have hydrocodone in it?

No. Hydrocodone and Codeine are two separate drugs with different chemical makeups.


What is the difference between codine and hydrocodone?

*codeine* is a naturally occurring opiate alkaloid found in poppies, hydrocodone is a semi-synthetic opioid sold most commonly under the brand name Percocet

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