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A phosphodiester bond are strong covalent bonds between a phosphate group and two 5-carbon ring carbohydrates over two ester bonds. A hydrogen bond is the electromagnetic attractive interaction between polar molecules where hydrogen is bound to a high electronegative atom. A phosphodiester bond is stronger than a hydrogen bond because of the covalent bonds.

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9y ago
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13y ago

No. Hydrogen bonds hold together the base pairs in DNA, and eventually the hydrogen bonds break due to torsion in DNA replication. Phosphodiester bonds hold together the nucleotide subunits of the DNA strand and do not fall apart unless they are cut with a restriction enzyme during transcription, etc.

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9y ago

A phosphodiester bond is a type of covalent bond. This strong bond is formed between two pentoses and a phosphate group above two bonds of ester.

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Q: What is the difference between phosphodiester bonds and hydrogen bonds?
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Related questions

What are the bonds that join the DNA sides?

Phosphodiester bonds.


What bond is between nucleic acids?

In producing a strand of DNA the nucleotides combine to form phosphodiester bonds.


What type of bond holds a nucleotide together and connects each nucleotide in a DNA strand?

The backbone of the nucleotides are composed of repeating ribose (in RNA) or deoxyribose (in DNA) and phosphates held together by phosphodiester bonds between the 5's and 3's of the ribose/deoxyribose.


How are nucleotides joined together within a single DNA strand?

I just did this paper in Biology, the answer is Hydrogen bonds! :)


What covalent bonds between the monomers of enzyme macromolecule are?

Phosphodiester bonds


What joined by adjacent nucleotides?

The nucleotides are joined together by phosphodiester linkages between the sugar of one nucleotide and the phosphate of the next.


What type of bonding is found in DNA?

DNA ( Deoxyribo Nucleic Acid) is held together by a hydrogen bond in between the two bases connecting the two backbones that make the "twisted ladder" shape. The backbones are held together by sugars and phosphates. They are usually called sugar-phosphate backbones.


How are nucleic acids held together?

Through covalent and hydrogen bonds. The covalent bonds hold the pentose sugar-phosphate backbone together and are alternatively called phosphodiester bonds. The hydrogen bonds are between the nitrogen bases and hold the "rungs" of the ladder together.


How are bonds between A-T and G-C different?

It is the hydrogen wich bonds between AT and GC the difference is in the number AT have 2 hydrogen bonds GC have 3 hydrogen bonds


What is phosphodiester?

A phosphodiester bond is a group of strong covalent bonds between a phosphate group and two 5-carbon ring carbohydrates (pentoses) over two ester bonds. Phosphodiester bonds are central to all life on Earth, as they make up the backbone of the strands of DNA.


What is the difference between AT and GC pairing?

A-T/U- only has two hydrogen bonds G-C- has three hydrogen bonds


Why do hydrogen and phosphorus mainly form covalent bonds?

The difference of electronegativity between hydrogen and phosphorus is not adequate to form ionic bonds.