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Substernal and retrosternal mean the same thing,: its an adjective describing the anatomical area below, beneath or behind the breast bone. Infrasternal is another term meaning the same thing but used less often. Pain there can indicate numerous different conditions from cardiac issues to swallowing problems caused by a yeast infection in the throat, hiatal hernias or esophageal spasms, to name a few. Only a dr. can tell you which one it is after exam and tests.

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