Time Release Technology also known as Sustained-release (SR), extended-release(ER, XR, or XL), time-release or timed-release, controlled-release (CR), or continuous-release (CR or Contin) pills are tablets or capsules formulated to dissolve slowly and release a drug over time. The advantages of sustained-release tablets or capsules are that they can often be taken less frequently than instant-release formulations of the same drug, and that they keep steadier levels of the drug in the bloodstream. The first Sustained release tablets were made by Howard Press, in Hoboken, NJ in the early 50's and the first tablets relased under his process patent were called "Nitroglyn" and made under license by Key Corp., in Florida. Today most are formulated so that the active ingredient is embedded in a matrix of insoluble substance (various: some acrylics, even chitin, these are often patented) so that the dissolving drug has to find its way out through the holes in the matrix. In some SR formulations the matrix physically swells up to form a gel, so that the drug has first to dissolve in matrix, then exit through the outer surface.
There are certain considerations for the formation of sustained release formulation:
The difference between controlled release and sustained release is that controlled release is a perfectly zero order release; that is, the drug releases over time irrespective of concentration. Sustained release implies slow release of the drug over a time period. It may or may not be controlled release.
Explain the difference between "Project Management" and "Delivery Management."
sustained release dosage form follows first order kinetics.
a controlled group is like an idea but an experiment that is controlled cannot be changed.
difference between local oscillator and controlled oscillator
The difference between a controlled variable and a variable is in their state. A controlled variable is something which is rigid and constant while a variable is liable to change and inconsistent.
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The difference between ordering and buying is In ordering you obtains the delivery service from the shop to your destination and in case of Buying you don't use delivery services offered by the company.
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because knowing what is the difference between objects and produres and data is important
NC is numerically controlled (hard wired) and CNC is computer numerically controlled.
walking:it is controlled by cerebellum reflex action:it is controlled by spinal cord
Delivery gap --The difference between the established standards and the actual quality of service delivered by employees