37 hours
The approximate drive time from Miami to Key Largo is: 1 hour and 27 minutes.
fort lauderdale
There are approximately 291.75 miles between Orlando, FL and Key Largo. The estimated driving time is 4 hours and 22 minutes.
The driving distance between Naples, FL and Key Largo, FL is approximately 150 miles. The driving time would be approximately 3 hours if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work and rush hour traffic in urban areas.)
92 miles.
The north end of Key Largo is Mile Marker 106 and Key West is located at Mile Marker 0 (although you reach the entry to the island around MM 3 or 4). It should take you about 2 hours, perhaps a little more depending on where in Key Largo you start.
Google Maps estimates the driving time as 77 minutes.
About 295 miles or four hours and forty five min. driving time
MapQuest estimates the driving time as 4 hours and 50 minutes.
545 miles.
The driving distance between Miami, FL and Key Largo, FL is approximately 63 miles. The driving time would be approximately 1 hour 15 minutes if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work, border crossings and rush hour traffic in urban areas.)
The closest major airport to Key Largo, Florida is Miami International Airport (MIA / KMIA). This airport is in Miami, Florida and is about 50 miles from the center of Key Largo, FL.